Which administration route is used for the drug Reclast?

Which administration route is used for the drug Reclast?

• A. Oral
• B. Inhalation
• C. Intravenous
• D. Topical

Answer: (C)

Reclast is zoledronic acid, a bisphosphonate used to treat osteoporosis and prevent skeletal events. It is given by intravenous infusion because there is no effective oral form and oral bioavailability of bisphosphonates is very poor, plus taking them by mouth can irritate the esophagus and stomach. Infusion delivers the drug directly into the bloodstream, providing predictable systemic exposure and allowing a convenient, usually yearly dosing schedule for osteoporosis. Inhalation and topical routes wouldn’t deliver the drug to the bones systemically, so they aren’t used for this purpose.

Reclast is zoledronic acid, a bisphosphonate used to treat osteoporosis and prevent skeletal events. It is given by intravenous infusion because there is no effective oral form and oral bioavailability of bisphosphonates is very poor, plus taking them by mouth can irritate the esophagus and stomach. Infusion delivers the drug directly into the bloodstream, providing predictable systemic exposure and allowing a convenient, usually yearly dosing schedule for osteoporosis. Inhalation and topical routes wouldn’t deliver the drug to the bones systemically, so they aren’t used for this purpose.