Which lipoprotein is considered 'bad' cholesterol?

Which lipoprotein is considered 'bad' cholesterol?

• A. HDL
• B. VLDL
• C. LDL
• D. Chylomicrons

Answer: (C)

Low-density lipoprotein is the lipoprotein that delivers cholesterol to tissues, including the arterial walls, which is why it’s labeled “bad” cholesterol. When LDL particles infiltrate the artery wall, they can become oxidized and are taken up by macrophages via scavenger receptors, forming foam cells and promoting atherosclerotic plaque. This direct contribution to plaque buildup and cardiovascular risk is the reason LDL carries that negative label. In contrast, HDL helps remove cholesterol from arteries and transport it to the liver for disposal, which is protective. VLDL mainly carries triglycerides and becomes LDL after triglyceride removal, and chylomicrons carry dietary fats; neither is singled out as “bad” in the same way.

Low-density lipoprotein is the lipoprotein that delivers cholesterol to tissues, including the arterial walls, which is why it’s labeled “bad” cholesterol. When LDL particles infiltrate the artery wall, they can become oxidized and are taken up by macrophages via scavenger receptors, forming foam cells and promoting atherosclerotic plaque. This direct contribution to plaque buildup and cardiovascular risk is the reason LDL carries that negative label. In contrast, HDL helps remove cholesterol from arteries and transport it to the liver for disposal, which is protective. VLDL mainly carries triglycerides and becomes LDL after triglyceride removal, and chylomicrons carry dietary fats; neither is singled out as “bad” in the same way.